The drug is used to treat Gastroesophageal Reflux Disease (GERD) and also is good for preventing further damage to the esophagus. Nexium, which is a proton pump inhibitor, also prevent stomach ulcers.
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Esomeprazole is the generic name of Nexium. It acts as a proton pump inhibitor which is responsible for the reduction of the acid which is produced inside the stomach.


Nexium is consumed for the treatment of GERD symptoms- gastroesophageal reflux disease and other medical conditions which consist of excessive acid in stomach for example Zollinger-Ellison syndrome. Also, it can be used to enhance the erosive esophagitis healing.

How to Use

Consume Nexium exactly in the way mentioned on the label, or as recommended by your physician.

Usually this drug is prescribed for just 4 to 8 weeks. Take each dosage with a full glass of water. Take this medicine at least an hour before having a meal.

The delayed-release nexium capsule shouldn’t be chewed or crushed. However to ease the process of swallowing, the capsule may be split open and the medicine can be sprinkled into a spoonful of apple sauce or pudding or applesauce. You should swallow at once without chewing. The mixture shouldn’t be kept for further use.

Nexium (Esomeprazole) 40mg capsules

Side Effects

Call your doctor if you see any side effects. The following are the side effects of Nexium:

  • Severe stomach pain,
  • Diarrhea;
  • Seizure (convulsions);
  • Joint pain or
  • Swelling accompanied by fever,
  • Swollen glands,
  • Skin rash on arms or cheeks;
  • signs of low magnesium - confusion; dizziness, fast/irregular heart rate; tremor/jerking movements in muscles; muscle spasms in hands/feet; feeling jittery; muscle cramps, coughing or choking feeling.
  • Kidney problems - More or less urination than usual, swelling, urine full of blood, rapid weight gain; or
  • Headache,
  • Mild diarrhea;
  • Drowsiness;
  • Stomach pain,
  • Constipation; or
  • Nausea,
  • Dry mouth.


Don’t use Nexium if you show hypersensitive response to esomeprazole or to similar drugs such as omeprazole (Zegerid, Prilosec), lansoprazole (Prevacid), rabeprazole (AcipHex) or pantoprazole (Protonix).

Usually, heartburn is confused by the initial heart attack symptoms. Get emergency healthcare attention if you observe chest pain or pain in the arm/shoulder, heavy feeling, nausea, a usual ill feeling or sweating.

Inform your specialist if you have any of the below mentioned serious medical conditions so that it is made sure that this drug is safe:

  • Severe liver disease;
  • Osteoporosis
  • Low magnesium levels in blood
  • Lupus;
  • Osteopenia

Utilizing a proton pump inhibitor like Nexium may enhance your risk of fracture of bone in the hip, spine or wrist. This impact has been seen mostly in patients who have consumed the drug at high dosage or longer term, and also in those patients who are above the age of 50. It is yet unclear if the actual reason behind the increased damage of fracture is nexium or not.

Pregnancy and Nexium

If nexium will hurt an unborn child or not, it is not yet certain but Let your specialist know if you have any plan or getting pregnant or are already pregnant.

It is quite uncertain whether nexium penetrates into maternal milk or could possibly cause damage to a nursing baby.

Drug Uses

Nexium drug is used to treat Gastroesophageal Reflux Disease (GERD). The drug decreases the quantity of acid produced in the stomach and thus preventing GERD. The drug is also good for preventing further damage to the esophagus. Nexium, which is a proton pump inhibitor, also prevent stomach ulcers.

How Taken

Nexium comes in capsule form and the general dosage is one daily. It should be taken an hour before the meal. Nexium should be swallowed whole. If there is difficulty in swallowing, open it and sprinkle the granules on applesauce and then take it. Take note that the granules should only be swallowed and not chewed or crushed.

Missed Dose

When missed your regular capsule, leave it or if you remember it in time, take it. But do not mix two dosages. And also if it is time for the next dosage, better skip the missed one and go with the regular dosage.

More Information

Well, before taking Nexium, you have to give details to your physician about all the medicines that you are taking.