Efudex is an antineoplastic is used for treating multiple actinic or solar keratoses, it works by blocking the growth of certain cells.
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Efudex belongs to the group of medicines called antineoplastics. It blocks the growth of certain cells and leads to the death of the cells.

Uses of Efudex

It is used to treat multiple actinic or solar keratosis. It is also used to treat pre-cancerous and cancerous skin growths

Side Effects of Efudex

Like all medicines, even Efudex can have certain side effects. Mostly there are no side effects, however, if you feel or observe any of the below side effects then contact your doctor immediately. Your doctor will let you know what can be done for such side effects. The common side effects of this medicine are

  • Crusting
  • Burning
  • Pain
  • Redness
  • Soreness
  • Irritation of the skin
  • Inflammation
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Other than these common side effects certain severe side effects can also occur in some cases. Side effects such as

  • Severe stomach pain
  • Vomiting
  • Diarrhea
  • Change in skin color
  • Fever
  • Chills
  • Rashes
  • Hives
  • Unable to breathe
  • Tightness in the chest
  • Sores on the treated area
  • Swelling of the mouth, face and lips
  • Severe burning sensation
  • Scarring
  • Redness
  • Crusting

There can be certain other side effects as well which may occur. It is advisable to contact your doctor in regards to any such concerns.

Contraindications of Efudex

This medicine should not be used by someone who is allergic to this medicine or if you have metabolic dihydropyridine dehydrogenase or DPD enzyme deficiency. Also, women who are pregnant or plan to become pregnant should not use this medicine. Consult your doctor about the safe use of this medicine. Inform your doctor about any prescription, non-prescription and herbal medicines which you are currently using. If you have any skin problems or if you are being treated for damaged or inflamed skin or if you have any open sores, then do not use this medicine. Like all medicines, even this one can interact with other medicines. If you are using the cream of this medicine, then make sure that you are using a non-metallic applicator or wear gloves while applying it. Wash the area gently where you have to apply the medicine. Wash your hands immediately after applying the medicine. Make sure that the medicine does not get into your eyes, nose mouth or genital area. If it goes into the eyes then make sure that you rinse your eyes with cool water. The complete healing of lesions may not occur for 1 to 2 months after you stop using the medicine. Avoid the sun as the treated areas stand a chance to get sunburned easily. Always check with your doctor before using this medicine. Use this medicine with caution in children and do not suggest this medicine to others even if they have similar conditions.

Pregnancy and Efudex

This medication is not safe to use during pregnancy. Only if the benefits of this medicine outweigh the risks involved it can be prescribed. Make sure that you use it under doctor`s supervision. It is not known if the medicine can pass into the breast milk. It may affect the baby, hence it is advisable not to use this medicine. You can still check with your doctor on this.

Cancer of skin can be treated with the use of Efudex medicine. It is also favorable in precancerous and help to stop the growth of cancerous growth. It belongs to the category of anti-metabolites medicine and works by reducing the growth of abnormal cells on the skin which are responsible for the skin cancer. Patient should read carefully prescription of the doctor and ask every question from doctor regarding medicine use. It is prescribed that wash your specific skin part properly and apply the medicine after drying it. Apply a thin form of layer on skin part and immediately wash your hand after medicine use. It is not recommended for those patients who feels allergic problem with this medicine or its ingredients. Pregnancy also caused some issue for the Efudex users so, patient should be aware about its complications during pregnancy. Moreover it is prohibited to use for metabolic disorder dihydropyrimidine dehydrogenase (DPD) enzyme deficiency patients.

Some medicine may interact with this drug if patient use along with it. It is far better to discuss with your doctor in such concern and do not start any other medicine without doctor advise. Be careful while applying the medicine on skin if you have burned or wounded skin. Similarly pregnancy, food and medicine allergy, use of herbal and supplements, breast feeding and use of other medicine are most important causes which may stop the use of Efudex. This cream can pass into the skin and involve into the blood stream where it can interact with the other medicine and serious problem can occur. Patient should wear the rubber glove before apply this cream on skin and it is better to wash gently that specific area where cream has to apply. Remove your gloves after applying the cream and wash your hands carefully. Do not cover the affected area with any bandage and use this cream only for external use except eyes, mouth, nose or genital area. As it is found that cream can pass the skin and can be mixed with the blood stream so it might create some sort of complication for pregnant women. It is better to discuss with your doctor while using in the pregnancy period. Similarly patient should not breast fee after apply this cream as it is not a good practice for the health of nursing baby. Do not keep this cream into the bathroom but in the room temperature away from the approach of children, heat and moisture. This article does not contain the complete list of side effects that is why patient should discuss with the doctor. Patient should use it according to the directions of the doctor because he or she better knows about its advantages for you.

Application of cream on skin must be according to doctor advice as it may depend on the patient condition or patient age. In case of any overdosing or any emergency medical aid, patient can contact to the poison helpline or with doctor. Dispose-off properly if you have any unused medicine.